Por favor, use este identificador para citar o enlazar este ítem:
https://hdl.handle.net/11000/30804
Food ProteineInduced Enterocolitis Syndrome in Adulthood: Clinical Characteristics, Prognosis, and Risk Factors
Ver/Abrir: Food ProteineInduced Enterocolitis Syndrome in.pdf
317,12 kB
Adobe PDF
Compartir:
Este recurso está restringido
Título : Food ProteineInduced Enterocolitis Syndrome in Adulthood: Clinical Characteristics, Prognosis, and Risk Factors |
Autor : González-Delgado, Purificación Muriel, Javier ![](/jspui/image/ORCID.jpg) Jiménez, Teodorikez Cameo, José Ignacio Palazón-Bru, Antonio ![](/jspui/image/ORCID.jpg) Fernández, Javier |
Editor : Elsevier |
Departamento: Departamentos de la UMH::Medicina Clínica |
Fecha de publicación: 2022-09 |
URI : https://hdl.handle.net/11000/30804 |
Resumen :
Food proteineinduced enterocolitis syndrome (FPIES) in adults is being increasingly recognized; however, little is known about its characteristics. OBJECTIVE: To describe the clinical characteristics, prognosis, and associated factors in adult FPIES. METHODS: A 10-year prospective study was conducted in the Allergy Section of Alicante General Hospital in adults diagnosed with FPIES. Detailed interviews with patients and oral food
challenges (OFCs) were performed to confirm diagnosis or evaluate for tolerance. Comorbidities and possible risk factors were analyzed retrospectively through electronic medical records to assess their association with the disease. RESULTS: One hundred and seven adults with FPIES (93.5% female) were followed for a median of 6.2 years. Abdominal pain was the most common manifestation (96.3%), followed by diarrhea (72%) and vomiting (60.7%). Seafood (59.8%), egg (14%), and milk (10.3%) were the most common triggers, whereas 43.9% reacted to more than 1 food group. We performed 49 OFCs: 9 to confirm diagnosis and 40 to evaluate for tolerance. After a median 3.5 years, 16.8% achieved tolerance. Resolution was correlated inversely with duration of
the disease (P[.04) and seafood (P[.023) but not with age of onset. The prevalence of gastrointestinal pathologies such as irritable bowel syndrome (IBS), eosinophilic esophagitis, inflammatory bowel disease, and celiac disease was higher than in the general population. A higher number of FPIES triggers were correlated with also having a diagnosis of IBS (P [ .02).CONCLUSIONS: Although adult FPIES normally persists, some
patients achieve tolerance. Adults with FPIES have a relatively high prevalence of gastrointestinal pathologies. The predominance of women may be related to hormonal factors. The clinical differences with pediatric FPIES warrant a revision of diagnostic criteria in adults.
|
Palabras clave/Materias: Food proteineinduced enterocolitis syndrome FPIES Adult FPIES Natural history Contraceptives Pregnancy Irritable bowel syndrome |
Tipo documento : application/pdf |
Derechos de acceso: info:eu-repo/semantics/closedAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
DOI : https://doi.org/10.1016/j.jaip.2022.05.006 |
Aparece en las colecciones: Artículos Medicina Clínica
|
La licencia se describe como: Atribución-NonComercial-NoDerivada 4.0 Internacional.