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Chapter 6: Characterization of TRPC Channels in a Heterologous System Using Calcium Imaging and the Patch-Clamp Technique


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Título :
Chapter 6: Characterization of TRPC Channels in a Heterologous System Using Calcium Imaging and the Patch-Clamp Technique
Autor :
De la Peña García, Elvira  
Gomis García, Ana María
Editor :
Humana Press imprint is published by the registered company Springer Science+Business Media, LLC part of Springer Nature.
Departamento:
Departamentos de la UMH::Fisiología
Instituto de Neurociencias
Fecha de publicación:
2019
URI :
https://hdl.handle.net/11000/30739
Resumen :
Transient receptor potential (TRP) ion channels are involved in a variety of fundamental physiological processes, and their malfunction produces numerous human diseases. Therefore, these proteins represent a class of attractive drug targets and a class of important off-targets for in vitro pharmaco...  Ver más
Palabras clave/Materias:
Ion channels
High-throughput screening
Ligand binding assay
Flux-based assay
Fluorescence- based assay
Drug discovery
Tipo de documento :
info:eu-repo/semantics/bookPart
Derechos de acceso:
info:eu-repo/semantics/closedAccess
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
DOI :
https://doi.org/10.1007/978-1-4939-9446-5
Publicado en:
TRP Channels Methods and Protocols Edited by Antonio Ferrer-Montiel Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, Alicante, Spain Tim Hucho Experimental Anesthesiology and Pain Research, Department of Anesthesiology and Intensive Care Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-9445-8 ISBN 978-1-4939-9446-5 (eBook) © Springer Science+Business Media, LLC, part of Springer Nature 2019
Aparece en las colecciones:
Artículos Fisiología



Creative Commons La licencia se describe como: Atribución-NonComercial-NoDerivada 4.0 Internacional.