Please use this identifier to cite or link to this item: https://hdl.handle.net/11000/30558
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dc.contributor.authorPerez-Sempere, Angel-
dc.contributor.authorVera-Lopez, Vanesa-
dc.contributor.authorGimenez-Martinez, Juana-
dc.contributor.authorRuiz-Beato, Elena-
dc.contributor.authorCuervo, Jesús-
dc.contributor.authorMaurino, Jorge-
dc.contributor.otherDepartamentos de la UMH::Medicina Clínicaes_ES
dc.date.accessioned2024-01-22T17:53:23Z-
dc.date.available2024-01-22T17:53:23Z-
dc.date.created2017-05-
dc.identifier.citationPatient Preference and Adherence Volume 11, 2017es_ES
dc.identifier.issn1177-889X-
dc.identifier.urihttps://hdl.handle.net/11000/30558-
dc.description.abstractPurpose Multidimensional unfolding is a multivariate method to assess preferences using a small sample size, a geometric model locating individuals and alternatives as points in a joint space. The objective was to evaluate relapsing–remitting multiple sclerosis (RRMS) patient preferences toward key disease-modifying therapy (DMT) attributes using multidimensional unfolding. Patients and methods A cross-sectional pilot study in RRMS patients was conducted. Drug attributes included relapse prevention, disease progression prevention, side-effect risk and route and schedule of administration. Assessment of preferences was performed through a five-card game. Patients were asked to value attributes from 1 (most preferred) to 5 (least preferred). Results A total of 37 patients were included; the mean age was 38.6 years, and 78.4% were female. Disease progression prevention was the most important factor (51.4%), followed by relapse prevention (40.5%). The frequency of administration had the lowest preference rating for 56.8% of patients. Finally, 19.6% valued the side-effect risk attribute as having low/very low importance. Conclusion Patients’ perspective for DMT attributes may provide valuable information to facilitate shared decision-making. Efficacy attributes were the most important drug characteristics for RRMS patients. Multidimensional unfolding seems to be a feasible approach to assess preferences in multiple sclerosis patients. Further elicitation studies using multidimensional unfolding with other stated choice methods are necessary to confirm these findingses_ES
dc.formatapplication/pdfes_ES
dc.format.extent5es_ES
dc.language.isoenges_ES
dc.publisherTaylor and Francis Groupes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectmultiple sclerosises_ES
dc.subjectmultidimensional unfoldinges_ES
dc.subjectpatient preferences,es_ES
dc.subjectdisease-modifying therapyes_ES
dc.subjectdecision-makinges_ES
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes_ES
dc.titleUsing a multidimensional unfolding approach to assess multiple sclerosis patient preferences for disease-modifying therapy: a pilot studyes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://doi.org/10.2147/PPA.S129356es_ES
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Artículos Medicina Clínica


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