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Reproductive toxicity: in vivo testing guidelines from OECD


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Título :
Reproductive toxicity: in vivo testing guidelines from OECD
Autor :
Estevan Martinez, Carmen  
Pamies, David
SOGORB, MIGUEL A
Vilanova, Eugenio
Editor :
Academic Espress
Departamento:
Departamentos de la UMH::Biología Aplicada
Fecha de publicación:
2022-02
URI :
https://hdl.handle.net/11000/30663
Resumen :
The guidelines for testing the reproductive toxicity in vivo developed and validated by Organisation for Economic Cooperation and Development allow for a systematic and internationally accepted testing and assessment of chemicals. Within reproductive toxicity two main categories of guidelines are usually identified: one dedicated to testing developmental toxicity, starting before the gestation period, while the other guidelines test the reproductive toxicity as a whole, therefore including male and female fertility and development. In this chapter, we summarize the guidelines on in vivo reproductive toxicity, by describing the general principles of the studies, the main aspects of the procedure, the endpoints and the observations, data reporting, and the criteria needed for the interpretation of their results.
Palabras clave/Materias:
Developmental toxicity
EndpointsIn
In vivo
OECD
Reproductive toxicology
Validated methods
Área de conocimiento :
CDU: Ciencias puras y naturales: Biología: Biología general y teórica
Tipo documento :
application/pdf
Derechos de acceso:
info:eu-repo/semantics/closedAccess
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
DOI :
https://doi.org/10.1016/B978-0-323-89773-0.00010-2
Aparece en las colecciones:
Libros /Capítulos de Libros- Biología Aplicada



Creative Commons La licencia se describe como: Atribución-NonComercial-NoDerivada 4.0 Internacional.