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dc.contributor.authorEstevan Martinez, Carmen-
dc.contributor.authorPamies, David-
dc.contributor.authorSOGORB, MIGUEL A-
dc.contributor.authorVilanova, Eugenio-
dc.contributor.otherDepartamentos de la UMH::Biología Aplicadaes_ES
dc.date.accessioned2024-01-26T09:21:18Z-
dc.date.available2024-01-26T09:21:18Z-
dc.date.created2022-02-
dc.identifier.citationReproductive and Developmental Toxicology (Third Edition) 2022, Pages 165-178es_ES
dc.identifier.isbn9780323897730-
dc.identifier.isbn9780323915601-
dc.identifier.urihttps://hdl.handle.net/11000/30663-
dc.description.abstractThe guidelines for testing the reproductive toxicity in vivo developed and validated by Organisation for Economic Cooperation and Development allow for a systematic and internationally accepted testing and assessment of chemicals. Within reproductive toxicity two main categories of guidelines are usually identified: one dedicated to testing developmental toxicity, starting before the gestation period, while the other guidelines test the reproductive toxicity as a whole, therefore including male and female fertility and development. In this chapter, we summarize the guidelines on in vivo reproductive toxicity, by describing the general principles of the studies, the main aspects of the procedure, the endpoints and the observations, data reporting, and the criteria needed for the interpretation of their results.es_ES
dc.formatapplication/pdfes_ES
dc.format.extent14es_ES
dc.language.isoenges_ES
dc.publisherAcademic Espresses_ES
dc.rightsinfo:eu-repo/semantics/closedAccesses_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectDevelopmental toxicityes_ES
dc.subjectEndpointsInes_ES
dc.subjectIn vivoes_ES
dc.subjectOECDes_ES
dc.subjectReproductive toxicologyes_ES
dc.subjectValidated methodses_ES
dc.subject.otherCDU::5 - Ciencias puras y naturales::57 - Biología::573 - Biología general y teóricaes_ES
dc.titleReproductive toxicity: in vivo testing guidelines from OECDes_ES
dc.typeinfo:eu-repo/semantics/bookPartes_ES
dc.relation.publisherversionhttps://doi.org/10.1016/B978-0-323-89773-0.00010-2es_ES
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