Please use this identifier to cite or link to this item: https://hdl.handle.net/11000/32543
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dc.contributor.authorBrinca, Ana Teresa-
dc.contributor.authorPeiró, Ana-
dc.contributor.authorMATALLIN EVANGELIO, PILAR-
dc.contributor.authorEleno, Irene-
dc.contributor.otherDepartamentos de la UMH::Farmacología, Pediatría y Química Orgánicaes_ES
dc.date.accessioned2024-07-18T10:09:00Z-
dc.date.available2024-07-18T10:09:00Z-
dc.date.created2024-06-29-
dc.identifier.citationInt. J. Mol. Sci. 2024, 25, 7177es_ES
dc.identifier.issn1422-0067-
dc.identifier.urihttps://hdl.handle.net/11000/32543-
dc.description.abstractInfertility is recognized globally as a social disease and a growing medical condition, posing a significant challenge to modern reproductive health. Endometriosis, the third-most frequent gynecologic disorder, is one of the most common and intricate conditions that can lead to female infertility. Despite extensive research, the etiology, malignant transformation, and biological therapy of endometriosis remain unknown. Blood and follicular fluid are two matrices that have been carefully studied and can provide insights into women’s health. These matrices are clinically significant because they contain metabolites closely associated with women’s illness stage and reproductive outcomes. Nowadays, the application of metabolomic analysis in biological matrices may be able to predict the outcome of assisted reproductive technologies with greater precision. From a molecular viewpoint on reproductive health, we evaluate and compare the utilization of human follicular fluid and blood as matrices in analysis for diagnostic and assisted reproductive technology (ART) predictors of success for endometriosis patients. In the follicular fluid (FF), plasma, and serum of endometriosis-affected women, researchers identified dysregulations of oxidative stress, upregulation of several immune factors, and aberrations in energy metabolic pathways. The altered signatures negatively correlate with the overall oocyte and embryo quality and fertilization ratees_ES
dc.formatapplication/pdfes_ES
dc.format.extent31es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectendometriosises_ES
dc.subjectinfertilityes_ES
dc.subjectbiomarkeres_ES
dc.subjectfollicular fluides_ES
dc.subjectserumes_ES
dc.subjectplasmaes_ES
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::615 - Farmacología. Terapéutica. Toxicología. Radiologíaes_ES
dc.titleFollicular Fluid and Blood Monitorization of Infertility Biomarkers in Women with Endometriosises_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.contributor.instituteInstitutos de la UMH::Instituto de Bioingenieríaes_ES
dc.relation.publisherversionhttps://doi.org/10.3390/ijms25137177es_ES
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Artículos Farmacología, Pediatría y Química Orgánica


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