Please use this identifier to cite or link to this item: https://hdl.handle.net/11000/30862
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dc.contributor.authorBertomeu-González, Vicente-
dc.contributor.authorCordero, Alberto-
dc.contributor.authorRuiz-Nodar, Juan Miguel-
dc.contributor.authorSánchez-Ferrer, Francisco-
dc.contributor.authorLópez-Pineda, Adriana-
dc.contributor.authorQuesada, José Antonio-
dc.contributor.otherDepartamentos de la UMH::Farmacología, Pediatría y Química Orgánicaes_ES
dc.date.accessioned2024-01-31T10:51:53Z-
dc.date.available2024-01-31T10:51:53Z-
dc.date.created2023-
dc.identifier.issn1879-1484-
dc.identifier.urihttps://hdl.handle.net/11000/30862-
dc.description.abstractBackground and aims Cardiovascular risk increases during menopause, so the medical and scientific community should consider women's specific risk factors to prevent cardiovascular disease. This study aims to assess the risk factors for the incidence of major adverse cardiovascular events (MACE) exclusive to postmenopausal women. Methods We conducted a prospective cohort study in postmenopausal women aged 40 years and older, who were included in the UK Biobank cohort between 2006 and 2010 and followed to 2021 (12 years). A total of 156,787 women were followed for a median of 12.5 years (nearly 2 million person-years), and MACE risk was assessed using Fine-Gray competing risk models. Results The cumulative incidence of cardiovascular morbidity and mortality was 1.2% (0.97 cases per 1000 women-years). Not having taken birth control pills, not having children, and early menarche (≤12 years) were independently associated with cardiovascular morbidity and mortality. Conclusions Risk factors for cardiovascular disease that are specific to women include early menarche, not having taken oral contraceptives, and reproductive history, and this relationship is independent of classic cardiovascular risk factors.es_ES
dc.formatapplication/pdfes_ES
dc.format.extent7es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.rightsinfo:eu-repo/semantics/closedAccesses_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectMenopausees_ES
dc.subjectCardiovascular diseasees_ES
dc.subjectMorbidityes_ES
dc.subjectMortalityes_ES
dc.subjectFemale risk factorses_ES
dc.titleRisk factors for major adverse cardiovascular events in postmenopausal women: UK Biobank prospective cohort studyes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://doi.org/10.1016/j.atherosclerosis.2023.117372es_ES
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Artículos Farmacología, Pediatría y Química Orgánica


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