Please use this identifier to cite or link to this item: https://hdl.handle.net/11000/33710

Prevalencia de asma en pacientes pediátricos alérgicos a animales

Title:
Prevalencia de asma en pacientes pediátricos alérgicos a animales
Authors:
Alberola García, Adrián
Tutor:
Canals Candela, Francisco José
Jiménez Maciá, Marina
Ibarra Maciá, Ángela
Editor:
Universidad Miguel Hernández
Department:
Departamentos de la UMH::Farmacología, Pediatría y Química Orgánica
Issue Date:
2024-05-02
URI:
https://hdl.handle.net/11000/33710
Abstract:
Introducción: El asma es la enfermedad crónica más frecuente en la infancia y los aeroalérgenos pueden ser un factor desencadenante de esta y de rinitis alérgica (RA). La prevalencia de sensibilización a alérgenos de perro y gato es elevada actualmente y la evidencia no ha esclarecido su papel como...  Ver más
Introduction: Asthma is the most common chronic disease in childhood and aeroallergens may be a trigger for asthma and allergic rhinitis (AR). The prevalence of sensitisation to dog and cat allergens is currently high and the evidence has not clarified its role as a risk factor for allergic asthma. Objective: We test the hypothesis that sensitisation to dog and/or cat allergens is associated with the development of asthma. Material and methods: A cross-sectional observational study was carried out with information from pediatric patients at the HGUE with asthma and/or AR sensitised to cat, dog, mite, salsola, olive tree and/or alternaria. We used data of the prevalence of asthma in the different sensitised groups as well as the intensity of asthma and AR symptoms and the asthma response to allergen immunotherapy (AIT). Results: We included 50 patients in whom no statistically significant differences were found for the prevalence of asthma between those allergic to animals and those allergic to other aeroallergens. However, a higher prevalence of sensitisation to animals was observed among those who lived with dogs and cats (75%) than among those who did not (17.4%) (p = 0.041). More cases of severe asthma were seen in those allergic to animals and of severe AR in those allergic to other aeroallergens without statistical significance. In the animal-allergic group, there is more asthma and severe AR in those polysensitised to cat and dog and in those allergic to cat compared to those allergic to dog. We also found a better response to AIT in cat-allergic versus dog-allergic people (p = 0.005). Conclusion: It is not certain that sensitisation to dogs and/or cats is associated with the development of asthma. Living with dogs and/or cats is a risk factor for sensitisation to those animal’s allergens. Cat-allergic asthma patients respond better to AIT than dog-allergic asthma patients.
Keywords/Subjects:
Asma
sensibilización
perro
gato
rinitis alérgica
ITA
Knowledge area:
CDU: Ciencias aplicadas: Medicina
Type of document:
info:eu-repo/semantics/bachelorThesis
Access rights:
info:eu-repo/semantics/openAccess
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Appears in Collections:
TFG- Medicina



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