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Phenotypic and functional characterization of glucagon-positive cells derived from spontaneous differentiation of D3-mouse embryonic stem cells


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Title:
Phenotypic and functional characterization of glucagon-positive cells derived from spontaneous differentiation of D3-mouse embryonic stem cells
Authors:
Vicente-Salar, Néstor  
Santana, Alfredo  
Juan-Picó, Pablo
Reig, Juan  
Roche, Enrique  
Editor:
Elsevier
Department:
Departamentos de la UMH::Biología Aplicada
Issue Date:
2013-01
URI:
https://hdl.handle.net/11000/30912
Abstract:
Background Glucagon expression is being considered as a definitive endoderm marker in protocols aiming to obtain insulin-secreting cells from embryonic stem cells. However, it should be considered that in vivo glucagon is expressed both in definitive endoderm- and neuroectoderm-derived cells. There...  Ver más
Keywords/Subjects:
cell culture
definitive endoderm
neuroectoderm
pancreatic hormones
stem cells
Knowledge area:
CDU: Ciencias puras y naturales: Biología
Type of document:
info:eu-repo/semantics/article
Access rights:
info:eu-repo/semantics/closedAccess
DOI:
https://doi.org/10.1016/j.jcyt.2012.08.002
Appears in Collections:
Artículos Biología Aplicada



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