Please use this identifier to cite or link to this item: https://hdl.handle.net/11000/30793
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dc.contributor.authorSignes-Pastor, Antonio Jose-
dc.contributor.authorDesai, Gauri -
dc.contributor.authorGarcía Villarino, Miguel-
dc.contributor.authorKaragas, Margaret R-
dc.contributor.authorKordas, Katarzyna-
dc.contributor.otherDepartamentos de la UMH::Salud Pública, Historia de la Ciencia y Ginecologíaes_ES
dc.date.accessioned2024-01-26T22:26:04Z-
dc.date.available2024-01-26T22:26:04Z-
dc.date.created2020-07-
dc.identifier.citationExposure and Health (2021) 13:173–184es_ES
dc.identifier.issn2451-9685-
dc.identifier.issn2451-9766-
dc.identifier.urihttps://hdl.handle.net/11000/30793-
dc.description.abstractLead (Pb), mercury (Hg), and fuoride (F) exposure during childhood is of concern owing to their toxicity. Also, evidence suggests that high and low exposure levels to manganese (Mn) and selenium (Se) during this vulnerable period are associated with an increased risk of adverse health efects. A reduced growth is associated with high Pb and F exposure; however, little is known about their impact on children’s body size, and there is a lack of consensus on the efects of Hg, Mn, and Se exposure on children’s anthropometric measures. This is particularly true for childhood metal co-exposures at levels relevant to the general population. We investigated the joint efects of exposure to a metal mixture (Pb, Mn, Hg, and Se in blood and F in plasma) on 6–11-year-old US children’s anthropometry (n=1634). Median F, Pb, Mn, Hg, and Se concentrations were 0.3 µmol/L, 0.5 µg/dL, 10.2 µg/L, 0.3 µg/L, and 178.0 µg/L, respectively. The joint efects of the fve metals were modeled using Bayesian kernel machine and linear regressions. Pb and Mn showed opposite directions of associations with all outcome measured, where Pb was inversely associated with anthropometry. For body mass index and waist circumference, the efect estimates for Pb and Mn appeared stronger at high and low concentrations of the other metals of the mixture, respectively. Our fndings suggest that metal co-exposures may infuence children’s body mass and linear growth indicators, and that such relations may difer by the exposure levels of the components of the metal mixture.es_ES
dc.formatapplication/pdfes_ES
dc.format.extent12es_ES
dc.language.isoenges_ES
dc.publisherSpringer Naturees_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectNHANESes_ES
dc.subjectChildhood exposurees_ES
dc.subjectMetal mixturees_ES
dc.subjectGrowthes_ES
dc.subjectBody sizees_ES
dc.titleExposure to a Mixture of Metals and Growth Indicators in 6–11‑Year‑Old Children from the 2013–2016 NHANESes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://doi.org/10.1007/s12403-020-00371-8es_ES
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Artículos Salud Pública, Historia de la Ciencia y Ginecología


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