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Cell Viability Effects and Antioxidant and Antimicrobial Activities of Tunisian Date Syrup (Rub El Tamer) Polyphenolic Extracts


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Título :
Cell Viability Effects and Antioxidant and Antimicrobial Activities of Tunisian Date Syrup (Rub El Tamer) Polyphenolic Extracts
Autor :
Dhaouadi, Karima
Raboudi, Faten
Estevan Martinez, Carmen  
Barrajón-Catalán, Enrique
Vilanova, Eugenio
Hamdaoui, Mohamed
Fattouch, Sami
Editor :
American Chemical Society
Departamento:
Departamentos de la UMH::Biología Aplicada
Fecha de publicación:
2010-12-14
URI :
https://hdl.handle.net/11000/31178
Resumen :
The aqueous−acetone polyphenolic extract of the traditionally derived date syrup, known as “Rub El Tamer”, was analyzed using RP-HPLC-DAD and ESI-MS. The phenolic content of the extract was 394.53 ± 1.13 mg per 100 g of syrup with caffeoylsinapylquinic acid as the most abundant compound (72.23%). The extract exhibited strong antioxidant activities as evaluated using the ABTS (2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)), DPPH (2,2-diphenyl-1-picrylhydrazyl) and FRAP (ferric reducing antioxidant power) methods. The extract antimicrobial potential against a range of microorganism strains showed that Staphylococcus aureus, Staphylococcus epidermidis, and Bacillus cereus were the most sensitive bacteria with MBC in the range of 0.5−0.05 mg/mL. Furthermore, in the presence of the syrup extract (8.18−131 μg/mL), the Human SH-SY5Y neuroblastoma and the 3T3 fibroblast cell lines showed dissimilar reduction of viability suggesting a higher cytotoxic effect against tumorigenic cells. Our results provide new insights into date syrup characterization which should stimulate further studies of this hot desert resource.
Palabras clave/Materias:
Antioxidant
antimicrobial
antiradical
cell viability
date syrup
polyphenols
RP-HPLC−MS
Área de conocimiento :
CDU: Ciencias puras y naturales: Biología
Tipo documento :
application/pdf
Derechos de acceso:
info:eu-repo/semantics/closedAccess
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
DOI :
https://doi.org/10.1021/jf103388m
Aparece en las colecciones:
Artículos Biología Aplicada



Creative Commons La licencia se describe como: Atribución-NonComercial-NoDerivada 4.0 Internacional.