Por favor, use este identificador para citar o enlazar este ítem: https://hdl.handle.net/11000/30730

Tailoring the plasmonic properties of gold-liposome nanohybrids as a potential powerful tool for light-mediated therapies


Vista previa

Ver/Abrir:
 3-Au.pdf

2,94 MB
Adobe PDF
Compartir:
Título :
Tailoring the plasmonic properties of gold-liposome nanohybrids as a potential powerful tool for light-mediated therapies
Autor :
Rubio-Camacho, Marta  
Martínez Tomé, María José
Cuestas Ayllon, Carlos  
de la Fuente, Jesús M.
Esquembre, Rocío  
Mateo , C. Reyes  
Editor :
Elsevier
Departamento:
Departamentos de la UMH::Agroquímica y Medio Ambiente
Fecha de publicación:
2022-12-20
URI :
https://hdl.handle.net/11000/30730
Resumen :
A fast and environmentally-friendly methodology has been developed by in situ synthesis of gold nanoparticles (AuNPs) on thermosensitive liposomes in different phase-states, obtaining nanohybrids with controllable and tunable plasmon modes within the visible/near-infrared region. Lipid phase, charge and synthesis temperature influence the final arrangement of AuNPs, so when the synthesis is performed on zwitterionic liposomes in fluid phase, discrete AuNPs with plasmon peaks in the visible region are obtained, while in gel phase AuNPs tend to aggregate forming nanoclusters, leading to plasmon bands gradually shifted to the infrared as the synthesis temperature decreases. The formed nanohybrids retain the physical properties of the liposomes (fluidity, degree of hydration, cooperativity) by maintaining the transition temperature in the mild-hyperthermia range, while preserving their light-to-heat conversion properties. Therefore, these nanohybrids can be considered excellent candidates as versatile photothermal agents with controlled drug delivery capacity, being powerful tools for light-mediated therapies.
Palabras clave/Materias:
In situ gold nanoparticles
Plasmonic nanohybrids
Thermosensitive liposomes
Tunable LSPR
Lipid phase-mediated AuNPs arrangement
Área de conocimiento :
CDU: Ciencias puras y naturales: Química
Tipo documento :
application/pdf
Derechos de acceso:
info:eu-repo/semantics/openAccess
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
DOI :
https://doi.org/10.1016/j.colcom.2022.100690
Aparece en las colecciones:
Artículos Agroquímica y Medio Ambiente



Creative Commons La licencia se describe como: Atribución-NonComercial-NoDerivada 4.0 Internacional.