Please use this identifier to cite or link to this item: https://hdl.handle.net/11000/27299

Evaluación de la validez y seguridad de criterios clínicos, analíticos y radiológicos en el diagnóstico de la COVID-19 en medio hospitalario


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Title:
Evaluación de la validez y seguridad de criterios clínicos, analíticos y radiológicos en el diagnóstico de la COVID-19 en medio hospitalario
Authors:
Ribes Mengual, Isabel
Tutor:
Ramos Rincón, José Manuel
Editor:
Universidad Miguel Hernández de Elche
Department:
Departamentos de la UMH::Medicina Clínica
Issue Date:
2021-10-04
URI:
http://hdl.handle.net/11000/27299
Abstract:
Evaluar la validez y seguridad diagnóstica de la combinación de criterios clínicos, analíticos y radiológicos en el diagnostico de COVID-19. Materiales y métodos. Estudio retrospectivo de pacientes ingresados por sospecha de COVID-19 entre marzo y abril de 2020. Se calculó la sensibilidad, especifi...  Ver más
Objective: To evaluate the validity and diagnostic safety of the combination of clinical, analytical and radiological criteria in the diagnosis of COVID-19. Material and methods: Retrospective study of patients admitted for suspected COVID19 between March and April 2020. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and positive likelihood ratio (LHR) were calculated for the clinical (fever, cough, dyspnea, arthromyalgia, asthenia, hypoxemia and anosmia / ageusia), analytical and radiological criteria, and their combination. Results: 313 consecutive patients were included, 115 (36.7%) with positive RT-PCR and 198 controls with negative RT-PCR (63.3%). The combination of clinical, analytical, and radiological criteria showed a sensitivity of 73.0%, specificity of 89.9%, PPV of 80.8%, NPV of 85.2%, and positive LHR of 7.2 for the diagnosis of SARS-CoV-2 infection in admitted patients. Conclusion: The combination of clinical, analytical and radiological criteria allows a reliable approach to the microbiological diagnosis of SARS-CoV-2 infection. This can be relevant in situations of scarce resources and in case of doubts about the need of repeating the RT-PCR if the first one is negative.
Keywords/Subjects:
COVID-19
SARS-CoV-2
Sensibilidad
Diagnóstico
España
Knowledge area:
CDU: Ciencias aplicadas: Medicina: Patología. Medicina clínica. Oncología
Type of document:
info:eu-repo/semantics/masterThesis
Access rights:
info:eu-repo/semantics/openAccess
Appears in Collections:
TFM-M.U Enfermedades Infecciosas y Salud Internacional



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