Título : Detección de la limitación respiratoria en fumadores mediante un sistema de puntos basado en parámetros sencillos |
Autor : Román Conejos, Esther |
Tutor: Cortés Castell, Ernesto Sánchez Mollá, Manuel |
Departamento: Departamentos de la UMH::Salud Pública, Historia de la Ciencia y Ginecología |
Fecha de publicación: 2019-04-12 |
URI : http://hdl.handle.net/11000/5142 |
Resumen :
En la actualidad no existe ningún método de cribado precoz establecido para la
Enfermedad Pulmonar Obstructiva Crónica (EPOC) en fumadores. Por tanto, se
presenta un modelo predictivo con parámetros sencillos que puede ser utilizado para la
detección temprana de EPOC en aquellos casos que cuenten y... Ver más
No validated screening method currently exists for Chronic Obstructive Pulmonary
Disease (COPD) in smokers. Therefore, we constructed a predictive model with simple
parameters that can be applied for COPD screening to detect fixed airflow limitation.
This observational cross-sectional study included a random sample of 222 smokers with
no previous diagnosis of COPD undertaken in a Spanish region in 2014–2016. The
main variable was fixed airflow limitation by spirometry. The secondary variables
(COPD factors) were: age, gender, smoking (pack-years and Fagerström test), body
mass index, educational level, respiratory symptoms and exacerbations. A points system
was developed to predict fixed airflow limitation based on secondary variables. The
model was validated internally through bootstrapping, determining discrimination and
calibration. The system was then integrated into a mobile application for Android. Fiftyseven
patients (25.7%) presented fixed airflow limitation. The points system included as
predictors: age, pack-years, Fagerström test and presence of respiratory symptoms.
Internal validation of the system was very satisfactory, both in discrimination and calibration. In conclusion, a points system has been constructed to predict fixed airflow
limitation in smokers with no previous COPD. This system can be integrated as a
screening tool, though it should be externally validated in other geographical regions
|
Notas: Programa de Doctorado en Salud Pública, Ciencias
Médicas y Quirúrgicas |
Palabras clave/Materias: Fumadores Enfermedad Pulmonar |
Área de conocimiento : CDU: Ciencias aplicadas: Medicina CDU: Ciencias aplicadas: Medicina: Farmacología. Terapéutica. Toxicología. Radiología |
Tipo de documento : info:eu-repo/semantics/doctoralThesis |
Derechos de acceso: info:eu-repo/semantics/openAccess |
Aparece en las colecciones: Tesis doctorales - Ciencias de la Salud
|