Abstract:
Introducción: La Paniculitis Mesentérica (PM) es un proceso inflamatorio crónico poco
frecuente que afecta al tejido adiposo mesentérico y cuya patogénesis aún se desconoce.
Puede ser primaria o secundaria, asociada a determinadas patologías como enfermedades
autoinmunes, neoplasias o infecciones. ... Ver más
Introduction: Mesenteric Panniculitis (PM) is a rare chronic inflammatory process that
affects the mesenteric adipose tissue and whose pathogenesis is still unknown. It can be
primary or secondary, associated with certain pathologies such as autoimmune diseases,
neoplasms or infections. Most patients are asymptomatic but non-specific gastrointestinal
symptoms such as abdominal pain, weight loss or altered intestinal rhythm may appear. The diagnosis is radiological, with CT being the most frequently performed test.
Treatment depends on the patient's symptoms.
Objectives: The main objective is to describe the clinical, sociodemographic, diagnostic
and evolutionary characteristics of all cases of PM that are under follow-up in the Internal
Medicine Service of the University Hospital of San Juan (HUSJ). The secondary
objective is to differentiate between primary PM and secondary PM, also making a
comparison of the clinical symptoms and evolution of both groups.
Material and methods: An observational, descriptive, retrospective study was carried
out on 111 patients with PM under follow-up by the Internal Medicine Service of the
HUSJ. Sociodemographic, clinical, analytical and radiological data were collected, as
well as information on follow-up. from the patients. A statistical analysis was performed
using SPSS, with descriptive measures for quantitative and qualitative variables, and the
Chi square test was used to analyze the relationship between qualitative variables.
Results: 111 patients participated, 56 men and 55 women. The average age of the
participants was 72.2 ± 13.07. 61.3% of patients have primary PM and 38.7% have
secondary PM. Of the patients with the latter, 44% are related to neoplasms, 42% to
infections and 14% to autoimmune diseases. 31.53% of our patients were asymptomatic,
abdominal pain was the most frequent symptom present in 58.9% of patients. Ultrasound
and abdominal CT were performed in 53.6% of patients. Only an abdominal CT scan was
performed in 41.8%. 85.6% of the patients had clinical stability, 3.6% had clinical
improvement, 2.7% worsened, and 8.1% died during the course of the disease. Conclusion: Mesenteric Panniculitis (PM) is a rare disease, in many cases idiopathic but
sometimes associated with infections, autoimmune diseases and neoplasias. It is
commonly detected incidentally by CT and can be asymptomatic in up to half of patients.
The prognosis is usually good.
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