Please use this identifier to cite or link to this item: https://hdl.handle.net/11000/31102
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dc.contributor.authorFalcó, Alberto-
dc.contributor.authorCartwright, Jamie R.-
dc.contributor.authorWiegertjes, Geert F.-
dc.contributor.authorHoole, David-
dc.contributor.otherDepartamentos de la UMH::Bioquímica y Biología Moleculares_ES
dc.date.accessioned2024-02-05T17:56:36Z-
dc.date.available2024-02-05T17:56:36Z-
dc.date.created2012-05-
dc.identifier.citationDevelopmental & Comparative Immunology Volume 37, Issue 1, 2012, Pages 127-138es_ES
dc.identifier.issn0145-305X-
dc.identifier.urihttps://hdl.handle.net/11000/31102-
dc.description.abstractC-Reactive protein (CRP) plays an important role in the acute phase response. Transcripts encoding two new CRP-like molecules (ccCRP1 and ccCRP2) from European common carp have been characterized which has enabled seven CRP-like genes to be identified in zebrafish. 79.3% (ccCRP1) and 74.5% (ccCRP2) identity to CRP from East-Asian common carp occurs and fish CRP genes form a distinct clade. ccCRP2 gene organization comprises four exons and three introns, in contrast to the two exons/one intron organization of mammalian CRP genes. Gene expression assays showed both ccCRP-like molecules are constitutively expressed in liver, skin, gill, gut, muscle, kidney, spleen and blood. Protein levels of ccCRP in serum and spleen were significantly different from other organs analyzed, and levels were greatest in the liver. It is proposed that the two carp CRP genes defined differ in their expression profiles which may suggest differences in their biological activities.es_ES
dc.formatapplication/pdfes_ES
dc.format.extent12es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.rightsinfo:eu-repo/semantics/closedAccesses_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectC-Reactive proteines_ES
dc.subjectCRPes_ES
dc.subjectImmune systemes_ES
dc.subjectCyprinus carpioes_ES
dc.subjectCarpes_ES
dc.subjectFishes_ES
dc.subject.otherCDU::5 - Ciencias puras y naturales::57 - Biologíaes_ES
dc.titleMolecular characterization and expression analysis of two new C-reactive protein genes from common carp (Cyprinus carpio)es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://doi.org/10.1016/j.dci.2011.10.005es_ES
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Artículos Bioquímica y Biología Molecular


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