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dc.contributor.authorMangas-Sanjuan, Carolina-
dc.contributor.authorde-Castro, Luisa-
dc.contributor.authorCubiella, Joaquín-
dc.contributor.authorDíez-Redondo, Pilar-
dc.contributor.authorSuárez, Adolfo-
dc.contributor.authorPellisé, María-
dc.contributor.authorFernández, Nereida-
dc.contributor.authorZarraquiños, Sara-
dc.contributor.authorNúñez-Rodriguez, Mª Henar-
dc.contributor.authorÁlvarez-García, Verónica-
dc.contributor.authorOrtiz, Oswaldo-
dc.contributor.authorSala-Miquel, Noelia-
dc.contributor.authorZapater, Pedro-
dc.contributor.authorJOVER, RODRIGO-
dc.contributor.otherDepartamentos de la UMH::Medicina Clínicaes_ES
dc.date.accessioned2024-01-31T13:17:50Z-
dc.date.available2024-01-31T13:17:50Z-
dc.date.created2023-08-29-
dc.identifier.citationAnnals of Internal Medicine • Vol. 176 No. 9 • September 2023es_ES
dc.identifier.issn1539-3704-
dc.identifier.issn1888-6760-
dc.identifier.urihttps://hdl.handle.net/11000/30890-
dc.description.abstractBackground: The role of computer-aided detection in identifying advanced colorectal neoplasia is unknown. Objective: To evaluate the contribution of computer-aided detection to colonoscopic detection of advanced colorectal neoplasias as well as adenomas, serrated polyps, and nonpolypoid and right-sided lesions. Design: Multicenter, parallel, randomized controlled trial. (ClinicalTrials.gov: NCT04673136) Setting: Spanish colorectal cancer screening program. Participants: 3213 persons with a positive fecal immunochemical test. Intervention: Enrollees were randomly assigned to colonoscopy with or without computer-aided detection. Measurements: Advanced colorectal neoplasia was defined as advanced adenoma and/or advanced serrated polyp. Results: The 2 comparison groups showed no significant difference in advanced colorectal neoplasia detection rate (34.8% with intervention vs. 34.6% for controls; adjusted risk ratio [aRR], 1.01 [95% CI, 0.92 to 1.10]) or the mean number of advanced colorectal neoplasias detected per colonoscopy (0.54 [SD, 0.95] with intervention vs. 0.52 [SD, 0.95] for controls; adjusted rate ratio, 1.04 [99.9% CI, 0.88 to 1.22]). Adenoma detection rate also did not differ (64.2% with intervention vs. 62.0% for controls; aRR, 1.06 [99.9% CI, 0.91 to 1.23]). Computer-aided detection increased the mean number of nonpolypoid lesions (0.56 [SD, 1.25] vs. 0.47 [SD, 1.18] for controls; adjusted rate ratio, 1.19 [99.9% CI, 1.01 to 1.41]), proximal adenomas (0.94 [SD, 1.62] vs. 0.81 [SD, 1.52] for controls; adjusted rate ratio, 1.17 [99.9% CI, 1.03 to 1.33]), and lesions of 5 mm or smaller (polyps in general and adenomas and serrated lesions in particular) detected per colonoscopy. Limitations: The high adenoma detection rate in the control group may limit the generalizability of the findings to endoscopists with low detection rates. Conclusion: Computer-aided detection did not improve colonoscopic identification of advanced colorectal neoplasias. Primary Funding Source: Medtronic.es_ES
dc.formatapplication/pdfes_ES
dc.format.extent9es_ES
dc.language.isoenges_ES
dc.publisherACP (American College of Physicians)es_ES
dc.rightsinfo:eu-repo/semantics/closedAccesses_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleRole of Artificial Intelligence in Colonoscopy Detection of Advanced Neoplasias. A Randomized Trial.es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://doi.org/10.7326/M22-2619es_ES
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