Resumen :
Las bacteriemias por microorganismos gram positivos son un evento frecuente en la
población adulta, con elevada mortalidad. Nuestro objetivo es analizar las características diferenciales y
mortalidad de las bacteriemias por Staphylococcus aureus, Enterococcus spp. y Streptococcus spp. así
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Background: Gram-positive bacteremia is a frecuent, high mortality associated event, in
the adult population. Our aim was to compare the clinical characteristics and mortality
of the Staphylococcus aureus, Enterococcus spp. and Streptococcus spp. bacteremia as
well as endocarditis determinant factors and time to blood culture positivity value.
Methods: Descriptive, retrospective analysis of 288 patients with gram-positive
bacteremia in a tertiary hospital from July 2016 to March 2018. We compared basal characteristics (demographic, clinical, therapeutical and microbiological data) along
with global, 30-day and 60-day mortality between microorganisms; as well as definite
endocarditis (Duke criteria).
Results: We included 228 patients with bacteremia, 98 of them were S. aureus, 58 were
Enterococcus spp. and 72 were Streptococcus spp. bacteremia. No statistical differences
were found in age (p=0,100) or 15-day mortality(p=0,266), as opposed to global
mortality, which was lesser for Streptococcus spp. bacteremia (p=0,026). We found
statistical differences in time to blood culture positivity (p=0,024) being longer
(median=13h) for the S. aureus bacteremia. Longer time to blood culture positivity was
independently associated to absence of endocarditis (n=17) (p=0,036/OR 0,786/IC 95:
0,628-0,984).
Conclusions: We observed higher mortality in S. aureus and Enterococcus spp.
bactereremia, against Streptococcus spp., finding time to blood culture to be an
independent factor for endocarditis. Nevertheless more studies are needed to verify
these findings.
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