Please use this identifier to cite or link to this item: https://hdl.handle.net/11000/30826
Full metadata record
DC FieldValueLanguage
dc.contributor.authorRuano-Zaragoza, Maria-
dc.contributor.authorSomoza, Maria Luisa-
dc.contributor.authorJimenez-Rodriguez, Teodorikez-
dc.contributor.authorSoriano Gomis, Victor-
dc.contributor.authorGonzález-Delgado, Purificación-
dc.contributor.authorEsteban-Rodriguez, Ángel-
dc.contributor.authorPalazón-Bru, Antonio-
dc.contributor.authorMiguel González, Blanca-
dc.contributor.authorFernández-Sánchez, Javier-
dc.contributor.otherDepartamentos de la UMH::Medicina Clínicaes_ES
dc.date.accessioned2024-01-30T10:50:12Z-
dc.date.available2024-01-30T10:50:12Z-
dc.date.created2020-12-
dc.identifier.citationInternational Archives of Allergy and Immunology . 2021;182(5):425-432.es_ES
dc.identifier.issn1423-0097-
dc.identifier.issn1018-2438-
dc.identifier.urihttps://hdl.handle.net/11000/30826-
dc.description.abstractBackground: Component-resolved diagnosis reveals the IgE response to many inhaled, food, and other allergens, improving the understanding and diagnosis of allergic diseases. Objective: The aims of the study are to study the recognition of different lipid transfer proteins (LTPs) and other allergen families in a large group of people sensitized to Pru p 3 and to analyze the relationship between the clinical entities and the allergens. Methods: This cross-sectional study included a large cohort of patients with positive skin tests to peach fruit and Pru p 3 specific IgE antibodies. Respiratory and food allergy symptoms were collected, and we performed prick tests with pollen, plant food, and other allergens plus the ImmunoCAP ISAC assay. Results: Our sample consisted of 421 people with a mean age of 33.25 years (range 16–68); 54.6% were women. Clinical entities included anaphylaxis (37.1%), urticaria (67.9%), and oral allergy syndrome (59.1%). Rhinitis, rhinoconjunctivitis, and/or asthma were diagnosed in 71.8% of the participants. The most pronounced correlation existed between sensitization to Pru p 3 and to Jug r 3, Pla a 3, Ara h 9, and Cor a 8. We found a higher incidence of anaphylaxis in people with 5 or more recognized LTPs. No association was observed between inhaled and food allergies. Conclusion: Most Pru p 3-sensitized participants were sensitized to additional allergens from the same family and, to a lesser extent, to other allergens, mainly in the profilin and PR-10 protein families. Anaphylaxis occurred in more than a third of the cases evaluated, and almost three-quarters of them had respiratory symptoms. Respiratory and food allergies involving LTPs do not seem to be associated.es_ES
dc.formatapplication/pdfes_ES
dc.format.extent8es_ES
dc.language.isoenges_ES
dc.publisherS. Karger AG, Baseles_ES
dc.rightsinfo:eu-repo/semantics/closedAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectLipid transfer proteinses_ES
dc.subjectPru p 3es_ES
dc.subjectComponent-resolved diagnosises_ES
dc.subjectAnaphylaxises_ES
dc.subjectRisk factorses_ES
dc.titleLipid Transfer Protein Sensitization: Risk of Anaphylaxis and Molecular Sensitization Profile in Pru p 3-Sensitized Patientses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://doi.org/10.1159/000511977es_ES
Appears in Collections:
Artículos Medicina Clínica


no-thumbnailView/Open:

 Lipid Transfer Protein Sensitization Risk of.pdf



370,07 kB
Adobe PDF
Share:


Creative Commons ???jsp.display-item.text9???